Chicken Alfredo Lasagna

Featured in: Everyday Table Meals

This luxurious chicken Alfredo lasagna combines tender shredded chicken breast with velvety Alfredo sauce, fresh spinach, and layers of gooey mozzarella and ricotta cheese between tender pasta sheets. The spinach mixture is enriched with eggs, Parmesan, and Italian herbs, creating a rich and satisfying filling. Baked until golden and bubbly, this dish feeds 8 people and takes just over an hour from start to table. Perfect for weeknight dinners or special occasions.

Updated on Sun, 18 Jan 2026 14:36:00 GMT
Golden-brown Chicken Alfredo Lasagna bubbling with creamy Alfredo sauce, tender chicken, and spinach between pasta layers in a white dish.  Save
Golden-brown Chicken Alfredo Lasagna bubbling with creamy Alfredo sauce, tender chicken, and spinach between pasta layers in a white dish. | platerelay.com

My oven timer went off right as my neighbor knocked on the door, and I panicked because the foil was still on. She ended up staying for dinner, and that slightly overbrowned top layer became the thing everyone fought over. Sometimes the best dishes come from a little chaos and good timing. This Chicken Alfredo Lasagna has been my answer to potlucks ever since, the kind of meal that makes people linger at the table. It turns a regular Tuesday into something worth remembering.

I made this for my sister after she had her second baby, and she texted me at midnight asking for the recipe. She said it was the first meal that didnt feel like an obligation, just pure comfort. Watching her eat it straight from the pan with a fork made me realize food does more than fill you up. It gives you a moment to breathe when everything else feels too fast.

Ingredients

  • Cooked chicken breast: Rotisserie chicken is your secret shortcut here, it adds a subtle roasted flavor and saves you from boiling and shredding.
  • Lasagna noodles: Oven ready noodles work beautifully and skip the boiling step, but if you use regular noodles, dont overcook them or theyll turn mushy under all that sauce.
  • Fresh baby spinach: It wilts down to almost nothing, so dont be shy with the two cups, and make sure its fully cooled before mixing or it will scramble the egg in your ricotta.
  • Onion and garlic: These build the base flavor, let the onion get translucent and soft, and the garlic should just start to smell sweet before you pull it off the heat.
  • Alfredo sauce: Homemade is lovely, but a good jarred version works when life is busy, just taste it first and add a pinch of nutmeg if it feels flat.
  • Ricotta cheese: Whole milk ricotta keeps things luscious, the egg binds it all together so it doesnt ooze everywhere when you slice.
  • Mozzarella and Parmesan: Mozzarella gives you that gooey pull, Parmesan adds sharpness and helps the top get golden and crispy.
  • Italian herbs: Dried works perfectly here, the baking time blooms the flavors, but if you only have fresh basil or oregano, use triple the amount.

Instructions

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Get your oven and dish ready:
Preheat to 375°F and grease your baking dish lightly so the edges dont stick. This step sounds small, but it makes serving so much easier later.
Cook your noodles if needed:
If youre using regular lasagna noodles, boil them until theyre just shy of tender, they finish cooking in the oven. Lay them flat on a towel so they dont clump together.
Sauté your aromatics and greens:
Soften the onion in a little olive oil, then add the garlic and let it perfume the kitchen for about a minute. Toss in the spinach and stir until it wilts and darkens, then set it aside to cool.
Mix your ricotta filling:
Combine ricotta, egg, half the Parmesan, herbs, salt, and pepper in a bowl until smooth. Fold in the cooled spinach mixture, making sure its evenly distributed.
Start your first layer:
Spread half a cup of Alfredo sauce on the bottom of your dish, it keeps the noodles from sticking and adds moisture. Lay down four noodles, slightly overlapping if needed.
Build the first hearty layer:
Spread half the ricotta spinach mixture over the noodles, then scatter half the chicken evenly. Drizzle a cup of Alfredo sauce and sprinkle two thirds of a cup of mozzarella on top.
Repeat the layering:
Add another four noodles, the remaining ricotta spinach, the rest of the chicken, another cup of Alfredo, and another two thirds cup of mozzarella. Each layer should feel generous and full.
Finish with the top layer:
Place the final four noodles, pour the remaining Alfredo sauce over them, and cover with the last of the mozzarella and Parmesan. This top layer gets beautifully golden, so dont skimp on the cheese.
Bake covered, then uncovered:
Cover tightly with foil and bake for 30 minutes so everything heats through and melds together. Remove the foil and bake another 20 to 25 minutes until the top is bubbly and browned in spots.
Rest before serving:
Let it sit for 10 to 15 minutes after pulling it from the oven, this helps it set so your slices hold their shape. Sprinkle fresh parsley on top if you want a little color and brightness.
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A slice of Chicken Alfredo Lasagna revealing cheesy mozzarella pull and creamy ricotta filling with spinach and chicken.  Save
A slice of Chicken Alfredo Lasagna revealing cheesy mozzarella pull and creamy ricotta filling with spinach and chicken. | platerelay.com

One evening my brother in law, who claims he only eats red sauce lasagna, had three servings and admitted this version might be better. That quiet confession across the table felt like winning a cooking award. Food has a way of softening opinions and opening people up to something new.

Making It Ahead

You can assemble this lasagna completely, cover it tightly, and refrigerate it for up to 24 hours before baking. Just add 10 extra minutes to the covered baking time since itll be cold from the fridge. I do this almost every time now because it makes dinner feel effortless, you just slide it in the oven and wait for the smell to fill the house. It also freezes beautifully for up to three months, thaw it overnight in the fridge before baking.

Choosing Your Chicken

Rotisserie chicken is my go to because it brings a little smokiness and saves so much time. If you poach your own, season the water with bay leaves and peppercorns so the chicken isnt bland. Leftover grilled chicken works too, especially if it has a little char on it. Whatever you use, make sure its shredded or diced small enough to nestle into the layers without creating big gaps.

Serving and Pairing

This lasagna is rich, so I always serve it with something bright and crunchy on the side. A simple arugula salad with lemon vinaigrette cuts through the cream perfectly. Garlic bread is tempting, but honestly, you dont need it, the layers are already so satisfying.

  • Let guests serve themselves from the pan, it stays warm longer and feels more relaxed.
  • A crisp white wine like Pinot Grigio or even a light sparkling water with lemon keeps things refreshing.
  • Leftovers can be portioned into individual containers and frozen for easy lunches that taste homemade.
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Homemade Chicken Alfredo Lasagna served fresh from the oven, garnished with parsley and perfect for a family dinner. Save
Homemade Chicken Alfredo Lasagna served fresh from the oven, garnished with parsley and perfect for a family dinner. | platerelay.com

This dish has become my reliable comfort, the one I make when I want to feel like everything is going to be okay. I hope it does the same for you.

Recipe FAQs

Can I prepare this lasagna ahead of time?

Yes, you can assemble the lasagna up to 24 hours in advance. Cover it with foil and refrigerate. Add 10-15 minutes to the baking time if baking from cold. You can also freeze it for up to 3 months before baking.

What's the best way to shred cooked chicken for this dish?

Use rotisserie chicken for the easiest option—simply pull the meat apart with two forks. Alternatively, poach or bake chicken breasts and shred them while still warm using two forks or a stand mixer with the paddle attachment on low speed.

Can I make my own Alfredo sauce instead of store-bought?

Absolutely. Melt 4 tablespoons butter, whisk in 3 tablespoons flour to create a roux, then gradually add 2 cups heavy cream while stirring. Add 1 cup Parmesan cheese, salt, pepper, and a pinch of nutmeg. This homemade version takes about 10 minutes.

How do I know when the lasagna is done baking?

The lasagna is ready when the top is golden brown, the edges are bubbling, and a knife inserted in the center comes out hot. Typically this takes 50-55 minutes total. If the top is browning too quickly, tent it with foil.

What vegetables can I substitute for spinach?

Kale, Swiss chard, or broccoli work wonderfully as spinach alternatives. You can also add diced zucchini, mushrooms, or sun-dried tomatoes for extra flavor and texture. Ensure any vegetables are well-drained before mixing into the ricotta filling.

Why is the resting time important after baking?

Allowing the lasagna to rest for 10-15 minutes lets the layers set and makes slicing cleaner and easier. This prevents the layers from sliding around on the plate and helps the cheese firm up slightly.

Chicken Alfredo Lasagna

Layered pasta with tender chicken, creamy Alfredo sauce, spinach, and melted cheese for an indulgent Italian-American comfort meal.

Time to Prep
30 minutes
Time to Cook
55 minutes
Total Duration
85 minutes
Created by Henry Foster

Recipe Category Everyday Table Meals

Skill Level Medium

Cuisine Italian-American

Makes 8 Portions

Dietary Details None specified

Ingredient List

Proteins

01 3 cups cooked chicken breast, shredded or diced

Pasta

01 12 lasagna noodles, regular or oven-ready

Vegetables

01 2 cups fresh baby spinach, roughly chopped
02 1 medium onion, finely diced
03 3 cloves garlic, minced

Sauces and Dairy

01 4 cups Alfredo sauce, store-bought or homemade
02 2 cups whole milk ricotta cheese
03 2 cups shredded mozzarella cheese
04 1 cup grated Parmesan cheese
05 1 large egg

Spices and Seasonings

01 1 teaspoon dried Italian herbs
02 1/2 teaspoon salt
03 1/4 teaspoon black pepper
04 2 tablespoons fresh parsley, chopped for garnish

Directions

Step 01

Preheat and prepare baking dish: Preheat the oven to 375°F. Lightly grease a 9x13-inch baking dish with cooking spray or butter.

Step 02

Cook lasagna noodles: If using regular lasagna noodles, cook according to package instructions until al dente. Drain and set aside on a clean surface.

Step 03

Sauté aromatics: Heat a skillet over medium heat with a splash of olive oil. Sauté diced onion for 3-4 minutes until softened. Add minced garlic and cook for 1 minute more until fragrant.

Step 04

Wilt spinach: Stir in chopped spinach and cook until wilted, approximately 2 minutes. Remove from heat and allow to cool slightly.

Step 05

Prepare ricotta mixture: In a medium bowl, combine ricotta cheese, egg, half of the Parmesan cheese, dried Italian herbs, salt, and black pepper. Mix in the cooled spinach mixture until well incorporated.

Step 06

Create first sauce layer: Spread 1/2 cup of Alfredo sauce evenly on the bottom of the prepared baking dish.

Step 07

Build first lasagna layer: Arrange 4 noodles over the sauce. Spread half of the ricotta-spinach mixture over noodles. Scatter half the shredded chicken on top. Drizzle with 1 cup of Alfredo sauce and sprinkle with 2/3 cup mozzarella cheese.

Step 08

Build second lasagna layer: Layer 4 additional noodles, then remaining ricotta-spinach mixture, followed by remaining chicken. Drizzle with 1 cup Alfredo sauce and sprinkle with 2/3 cup mozzarella cheese.

Step 09

Top final layer: Arrange final layer of 4 noodles on top. Pour remaining Alfredo sauce over noodles. Sprinkle remaining mozzarella cheese and remaining Parmesan cheese evenly across the surface.

Step 10

Bake covered and uncovered: Cover baking dish with aluminum foil and bake for 30 minutes. Remove foil and bake an additional 20-25 minutes until the top is bubbly and golden brown.

Step 11

Rest and serve: Remove from oven and let stand for 10-15 minutes before slicing. Garnish with fresh parsley if desired.

Equipment Needed

  • 9x13-inch baking dish
  • Large skillet
  • Medium mixing bowl
  • Saucepan for Alfredo sauce preparation
  • Measuring cups and spoons
  • Aluminum foil

Allergy Advice

Always check every ingredient for potential allergens. Ask your doctor if you're unsure.
  • Contains wheat from pasta
  • Contains milk and milk products
  • Contains egg
  • May contain tree nuts if using nut-based Alfredo sauce

Nutrition Info (per serving)

For reference only—please consult a nutritionist or healthcare provider for dietary advice.
  • Caloric Value: 510
  • Fat Content: 27 grams
  • Carbohydrate: 33 grams
  • Proteins: 34 grams